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The BBB model was integrated in a microfluidic network, made largely of polydimethylsiloxane (PDMS), a transparent, gas-permeable soft polymer that has been widely used for the fabrication and prototyping of microfluidics-based organ-on-chip platforms 26,27,28,29 owing to its ease of handling, fast turn-around time, and high biocompatibility

For people who already have enough B12, their red blood cells are already working properly, and the body simply gets rid of any extra B12 it doesnt need

The loss of dopamine neurons in the midbrain substantia nigra causes resting tremor, bradykinesia, and stiffness (30)

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