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Disruption of calcium homeostasis can trigger mitochondrial dysfunction and increased ROS production

These properties suggest it might be studied in contexts of cellular age-associated degeneration, neuroinflammation, ischemia-reperfusion research, or chronic inflammatory disorders

doi: 10.1136/bmj.303.6809.1026 [PubMed] 02748061 Riggs BS, Bronstein AC, Kulig K, Archer PG, Rumack BH

predictions help to reduce the costly experimental approach [24]

Favalli EG (2020) Understanding the role of interleukin-6 (IL-6) in the joint and beyond: a comprehensive review of IL-6 inhibition for the management of rheumatoid arthritis

Tanezumab: Tanezumab is a humanized monoclonal antibody against NGF