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Synergistic effects of liposomes encapsulating atorvastatin calcium and curcumin and targeting dysfunctional endothelial cells in reducing atherosclerosis

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These changes were accompanied by inflammatory alterations in the intestinal mucosa and elevated levels of lipopolysaccharides (LPS), which activate TLR4-dependent inflammatory pathways and contribute to -cell damage (Vatanen et al., 2018)

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NNMT is an enzyme that methylates nicotinamide (vitamin B3) using S-adenosylmethionine (SAM) as a methyl donor

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