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The ideal time to take MSM is before a meal although it can also be taken with food depending on individual sensitivity

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Subsequently, the rats were administered DMSO (control) or the different doses of AST (e.g., 5, 10, and 15 mg/kg) over the next 6 weeks

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Some limitations include high costs, low yield, potential skin irritation, sufficient solubility, and size for effective percutaneous absorption [136]