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Mechanistic investigations associate these outcomes with signaling pathways involving vascular endothelial growth factor receptor-2 (VEGFR-2) and downstream Akt-eNOS activation, processes that collectively facilitate efficient muscle tissue remodeling (5)

This reprogramming involves dynamic shifts between glycolysis, the TCA cycle, and oxidative phosphorylation and is influenced by both intrinsic signaling pathways and extrinsic factors such as steroid hormones

Conjugated secondary 12-hydroxylated bile acids promote liver fibrogenesis

doi:10.3748/wjg.15.5121

Ferroptosis-strengthened metabolic and inflammatory regulation of tumor-associated macrophages provokes potent tumoricidal activities

Psychiatry 11 , 328 (2021)