Both vial and pen formulations should never be frozen, as ice crystal formation can damage the medication's molecular structure and render it ineffective
Are all three available in Canada
It is supplied in lyophilised (freeze-dried) form to ensure maximum stability and shelf life
[11] In practice, the benefit of treating a true B deficiency in pregnancy, preventing anemia and neurological injury, is considered to far outweigh any theoretical risks, under the guidance of a healthcare professional
Subcutaneous injection remains the preferred administration route for systemic effects, providing 90-95% bioavailability
There are more nerves in the muscle in the thigh than in the deltoid muscle, and it is easier to find the safe place to do the injection in the upper arm (which is why this is a common used place to give vaccinations i.m.)