Oxidative stress characterized by an imbalance between the generation of reactive oxygen species (ROS) and antioxidant defences
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Albarakati M, El-Tholoth HS, Alzahrani A, Alghamdi OS, Alquliti A, Alnuami M
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The cell-type-specific impact of cuproptosis creates a dualistic injury pattern: it directly causes acute loss of contractile and endothelial function by eliminating cardiomyocytes and ECs, while simultaneously driving chronic maladaptive remodeling through the activation of resistant VSMCs and fibroblasts [154, 157]
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