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Long-term risk of depressive and anxiety symptoms after early bilateral oophorectomy

Only a smaller number of cells develop under standard culture conditions when either vitamin B2, B6, or B9 is present

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Multiple cellular processes are considered to contribute to this functional decline and these are collectively referred to as the hallmarks of aging and these include processes like genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, disabled macroautophagy, deregulated nutrient-sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, altered intercellular communication, chronic inflammation, and dysbiosis 1