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Given the promising anti-cancer effects of IGF-IR-targeted agents in preclinical models, clinical trials have been initiated to evaluate the efficacy of anti-IGF-IR mAbs (Table 1) [144,145,146,147,148,149,150,151]

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Noh HS, Hah YS, Nilufar R, Han J, Bong JH, Kang SS, et al

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66 , e0239521 (2022)

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Ichimura Y, Waguri S, Sou Y-S, Kageyama S, Hasegawa J, Ishimura R, et al

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NO (nitric oxide) pathway In vitro studies have observed that BPC-157 can modulate nitric oxide synthase (NOS) activity in various cell models

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Ramirez-Carrozzi VR, Braas D, Bhatt DM, Cheng CS, Hong C, Doty KR et al

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