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Gingival crevicular fluid shows significantly reduced GSH concentrations and markedly elevated 4-HNE levels ( 2.4 The ferroptosis-inflammation vicious cycle drives chronic periodontitis Growing evidence indicates that ferroptosis can trigger inflammatory responses, while the inflammatory microenvironment further promotes ferroptosis, forming a self-amplifying vicious cycle that drives the persistent progression of chronic periodontitis
For example, the gastrointestinal tract of poultry (chickens, turkeys, ducks) differs markedly from that of monogastric mammals (pigs, mice, rats, rabbits) in terms of transit time, pH, and microbial composition (19)
10.1007/BF02408436 44
Mutant huntingtin impairs immune cell migration in Huntington disease
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Accordingly, animal models for genes of a syndromic disorder were commonly found to present autistic traits including Fragile X (FMR1) with social interaction deficits, hyperactivity, and cognitive impairments (Willem Verhoeven, 2011
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