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From the genetics angle, there are some pediatric, congenital causes of 5-oxoprolinuria which not surprisingly involved defects in enzymes of the gamma-glutamyl cycle (in particular, mutations in glutathione synthetase and 5-oxoprolinase have been identified in these patients).

KrancWBudnaJKahanRChachulaABryjaACiesiolkaSet al

Kelso GF, Maroz A, Cochem HM, Logan A, Prime T.A, Peskin AV, et al., A mitochondria-targeted macrocyclic Mn(II) superoxide dismutase mimetic, Chem Biol 2012:19: 12371246

Mice lacking a functional SELENOF were found to develop nuclear cataract (lens opacification) at a very early age suggesting that SELENOF may be critical to the quality control system of protein folding in the lens (33)

The survival rate and weight were calculated followed by delineation of survival and weight curve

Can I just take Glutathione orally