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Researchers also noted a 54% improvement in skin tone and 59% improvement in skin homogeneity beginning at week 2 and continued after 12 weeks of daily serum application

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Contrary to claudin-1, which in normal colonic epithelial cells is expressed to a minimum (even though it is highly increased in colon cancer tissue and cells 65 ), the claudin-7 protein is highly expressed in the colonic epithelium

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