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Fruzaqla targets the VEGF-1, -2 and -3 receptors, which together play a crucial role in the formation of the blood vessels that sustain tumors

Belosic Halle Z, Vlainic J, Drmic D, Strinic D, Luetic K, Sucic M, et al

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residue Ri including without limitation, tyrosine, phenylalanine, aspartic acid, arginine, isoleucme, serine, histidine, glycine, cysteine, methionine, tryptophan, norvaline, ornithine, S-benzyl cysteine amino acid residues

Subsequently, unique gene hit counts were calculated using featureCounts from the Subread package v.1.5.2 by summarizing and reporting the hit counts based on the gene id feature in the annotation file 26