doi: 10.1093/ecco-jcc/jjaa014
For example: Growth hormone-releasing peptides (GHRPs) stimulate pituitary cells specifically to secrete growth hormone Neuropeptides like Semax modulate brain-derived neurotrophic factor (BDNF) expression in neurons Body protective compounds like BPC-157 interact with growth hormone receptors in the gastric mucosa The specificity-potency combination is what distinguishes bioactive peptides from broader pharmacological agents
The biological rationale is interesting but unproven
The results were significant: At 48 weeks, participants receiving the 12 mg dose achieved a mean weight reduction of 24.2% (approximately 58 pounds or 26.2 kg) 100% of participants on the 8 mg or 12 mg doses lost at least 5% of their body weight More than 90% of participants on the 12 mg dose lost at least 10% of their body weight Nearly half of participants on the highest dose lost 25% or more of their body weight The study also showed improvements in cardiometabolic markers including blood pressure, triglycerides, LDL cholesterol, and fasting glucose
By promoting the development of new capillaries in injured areas, these peptides ensure that healing cells receive the oxygen and nutrients they need to repair tissue effectively
Most patients notice reduced inflammation and improved function within 2 to 3 weeks
