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Injectable and liposomal forms may achieve higher systemic levels, though clinical evidence supporting superiority over oral formulations remains limited

doi: 10.1164/rccm.202303-0558WS 4 BerstenADEdibamCHuntTMoranJ

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If significant insomnia occurs at 2.5 mg, other factors (stress, pre-existing sleep issues, caffeine, screen habits) are more likely responsible than the medication itself