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The gut-brain axis is a bidirectional neurohumoral communication system between the CNS and the enteric nervous system (Collins et al., 2012)

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Functional expression of the lymphoid chemokines CCL19 (ELC) and CCL 21 (SLC) at the bloodbrain barrier suggests their involvement in G-protein-dependent lymphocyte recruitment into the central nervous system during experimental autoimmune encephalomyelitis

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