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Given their non-invasive nature, accessibility, and cost-effectiveness of sublingual formulations, they may represent a promising approach for long-term B12 management, particularly in patients with impaired absorption or in resource-limited settings

If left untreated, it can also lead to neurological damage

This targeted mechanism allows enhanced fat oxidation and reduced lipogenesis, particularly in visceral and abdominal fat depots, making it a key subject in obesity and metabolic optimization research

Additional studies describe exploratory evaluation of intracellular signaling dynamics, NAD-related metabolic networks, and methylation-associated processes examined in non-clinical research settings