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The metabolite -KG induces GSDMC-dependent pyroptosis through death receptor 6-activated caspase-8

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Yang B, Damodaran S, Khemees TA, Filon MJ, Schultz A, Gawdzik J, et al

Large-scale CQD synthesis is often hindered by batch-to-batch variability, impurity profiles, and contamination risks, emphasising the need for standardised, GMP-compliant synthesis protocols and robust quality control frameworks [178]

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