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Examined in stress-adaptation models: Chronic stress alters neural plasticity and disrupts sleep patterns

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100200 mcg once daily, titrated upward gradually across an 812 week course (about ~0.71.4 mg per week )

Though functional roles of the VGF peptides detected here remain to be established, consistent changes in VGF abundance across proteoforms between diagnostic classes in the present study, as well as previous literature, suggest clear roles of VGF peptides in cognitive functioning 15