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For example, an octapeptide (IKFQFHFD)-based biocompatible hydrogel demonstrated acidic pH-responsive release at pH 5.5, leading to effective biofilm eradication and activation of wound healing via membrane and cell wall disruption mechanisms [153]

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This is the window most researchers use for primary outcome measurement

For example, Icarin was confirmed to inhibit ECM degradation and ferroptosis in chondrocytes, thereby alleviating articular cartilage damage in OA rats by restoring SLC7A11 and GPX4 expression (Xiao et al., 2024)

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