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Regarding SLC transporters, reduced folate carrier (RFC), proton-coupled folate transporter (PCFT), organic anion transporter 3 (OAT3), and organic anion transporting polypeptide 1A2 (OATP1A2) all transport MTX as a substrate (Badagnani et al
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Researchers study this combination to examine dual-pathway GH stimulation, pulsatile versus sustained release patterns, and interactions between the hypothalamic GHRH pathway and the gastric ghrelin signaling system
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