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Here we describe some of the most characterized examples: Ethacrynic acid and analogues Ethacrynic acid (EA)an ,-unsaturated ketone used as diuretic drugis a common substrate/inhibitor of several GSTs (Fig
Treatment with ITCs and BSO A
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However, adverse effects may limit the treatment potential, e.g., glitazones are associated with phenotypical weight gain [136] and obeticholic acid induced pruritus and elevated LDL-C [137], the latter a potential concern in patients already at risk for cardiovascular disease
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Eur Rev Med Pharmacol Sci 20:16561663 Grandi G, Pignatti L, Ferrari F, Dante G, Neri I, Facchinetti F (2017) Vaginal alpha-lipoic acid shows an anti-inflammatory effect on the cervix, preventing its shortening after primary tocolysis
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