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After 1 month of treatment in pernicious anemia patients, the once weekly dosing of 500 mcg B12 intranasal gel resulted in a statistically significant increase in B12 levels when compared to a once monthly 100 mcg IM dose

Considerations for Patients with Neurological Manifestations Those with nerve or brain problems from Vitamin B12 lack often need strong treatment

These compounds work together to enhance fat metabolism and energy production

This is particularly relevant for patients with pernicious anaemia, where intrinsic factor deficiency prevents adequate oral absorption

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