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These confounding variables make it difficult to isolate intrinsic effects of aging in experimental models

Figure 1 shows that fecal water content in aging rats with FC was significantly increased, prompting the examination of aquaporin (AQP) levels related to water reabsorption in intestinal contents

doi: 10.3390/ani10122281 91 SafaS.MoghaddamG.JozaniR

MTRR and MTHFR polymorphism: link to Down syndrome

Importantly, these mutations also led to the loss of recognition by a wide panel of monoclonal antibodies undergoing testing in the clinic [70]

The TIMP has shown good predictive validity for later neurodevelopmental outcomes.41 We will pilot the test in the current study setting ahead of study start to ensure that it is appropriate for the study setting