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Vincent van Gogh, Public domain, via Wikimedia Commons Yet another of Van Goghs paintings to feature a skeleton is the pencil-on-cardboard sketch titled Hanging Skeleton and Cat (1886)

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Some suspected substances include volatile organic compounds that can do damage to the liver, kidneys and nervous system, and formaldehyde, which can cause cancer

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Instead, he wanted the development to feel like it came out of left field, as he explained: This approach interestingly makes Serenity a bit different than most twist-centric features, in that its not the kind of movie where you go back to see it a second time and read everything differently than you did before you fully knew where the story was going