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Sequence: The structure of PE-22-28 is a simplified portion of galanin, retaining the functional activity that interacts with galanin receptors while removing portions that can create unwanted or overlapping effects

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USF1 and USF2, but not c-Myc, can bind to this E-box and overexpression of either one can inhibit the promoter activity (Cheng et al., 2005)