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Subsequently, whole exome sequencing (WES) of simplex families with one affected child demonstrated strong association of rare de novo exonic single nucleotide variants (SNV) with ASD [20,21,22,23,24], with more recent analyses highlighting around a hundred genome-wide significant ASD risk genes [25, 26]

Circ Res 54(6):694702 Saez LJ, Gianola KM, McNally EM, Feghali R, Eddy R, Shows TB, Leinwand LA (1987) Human cardiac myosin heavy chain genes and their linkage in the genome

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3 RACE Total RNA was isolated using Trizol from pPASPORT-transfected cells and 1 g of total RNA was used to perform reverse transcription using 3RACE-RT primer and M-MLV (Promega) in 20 l reaction

The effect of vitamin C (ascorbic acid) in the treatment of patients with cancer: a systematic review

How inhibition of nucleotide metabolism impacts non-apoptotic cell death is less clear