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10.1126/sciadv.ads5466 108 RozierR.PaulR.Madji HounoumB.VillaE.MhaidlyR.ChicheJ.et al (2021)

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Lipid peroxides are formed when lipids (such as those in cell membranes) are subject to oxidative damage from ROS and other free radicals

The illness is characterized by gradual loss of dopaminergic neurons in the substantia nigra and the appearance of Lewy bodies, which include aggregation of alpha-synuclein, extensively dispersed proteins in the cerebral tissues