[2,9] This connection between gut-derived peptides and neurological function is an active area of investigation
Nausea (most common, especially during first 1 to 2 weeks of a new dose) Diarrhea or, just as often, constipation Vomiting (less common but more likely at 9 to 12 mg) Reduced appetite, food noise quieting down (this is the goal, not a side effect) Skin sensitivity (dysesthesia): tingling, prickly feeling, or sunburn-like skin
Figure 2 3.5 GDC increases extracellular, but not intracellular, alkaline phosphatase activity To study the effects of GDC on epithelial function, the intracellular and extracellular alkaline phosphatase activity were measured in GDC treated Caco-2/HT29-MTX monolayers (Figures 2B, C)
Shaking creates foam, which means air bubbles trapped against peptide molecules
UK guidance emphasises the importance of prompt, adequate treatment of confirmed B12 deficiency to prevent irreversible neurological harm
AMPK activation (AICAR): a well-characterised AMP-activated protein kinase agonist used extensively in cellular energy-sensing research