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It has been investigated for its effects on tendon-to-bone healing, gastrointestinal mucosal integrity, vascular development, and modulation of nitric oxide and growth-factor pathways in animal models

doi: 10.3390/ijms19071987

Signs of Vitamin B12 Deficiency Some common signs that you may be deficient in Vitamin B12 include fatigue or tiredness, weakness, difficulty concentrating or thinking clearly, pale skin, dizziness or light-headedness, loss of appetite, weight loss, constipation or diarrhea, numbness or tingling in the hands and feet, sore tongue, headaches and vision problems

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Two primary areas emerge from the data as being critical for longevity: gut barrier integrity and metabolic function, especially as it relates to GLP-1