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The consent forms will be filled up by study gynaecologists or supervisors, preferably in the presence of the husband

Author contributions Both authors contributed to the manuscript conception and design, read and critically reviewed and revised the work, approved the final submitted manuscript, and agree to be accountable for the work

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In our opinion, when considering a new compound for clinical testing, it is important to have in vivo and in vitro studies confirming positive effects suggested by gene profiling as well as safety

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