Several factors can impair B12 absorption: Reduced stomach acid production (achlorhydria or hypochlorhydria), common in older adults and those taking proton pump inhibitors or H2-receptor antagonists long-term, impairs the release of B12 from food proteins Pernicious anaemia , an autoimmune condition destroying parietal cells and reducing intrinsic factor production, completely blocks the primary absorption pathway Gastrointestinal disorders including Crohn's disease, coeliac disease, or surgical removal of stomach or ileum sections directly damage absorption sites Metformin , commonly prescribed for type 2 diabetes, may reduce B12 absorption through unclear mechanisms
At Onus, Methylcobalamin is our most commonly used form of B12 for injection
It helps ensure safe and effective treatment
Common places to inject include the deltoid, vastus lateralis, and gluteal muscles
Methylcobalamin is the naturally occurring, active form of Vitamin B12. Unlike synthetic forms (such as cyanocobalamin), which the body must actively convert before using, methylcobalamin is ready to be absorbed and utilized immediately, offering faster and more reliable energy support
This is especially true if you are a vegan, are older than age 50 and of African American or Northern European descent, have an autoimmune disorder, or have had your stomach removed
