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10.3390/ijerph16162864 Int

Accessed 10 Apr 2026

It is also important to explore potential therapeutic strategies aimed at restoring inter-organellar integration through small molecules, redox-signaling modulators, and inhibitors of calcium overload

Importantly, low Se status has been associated with adverse pregnancy outcomes such as miscarriages, neural tube defects, premature birth, low birth weight, preeclampsia, glucose intolerance, gestational diabetes, and even diaphragmatic hernia [7,8,9,10], albeit its precise role in the etiology of these complications has yet to be clarified

Nuclear ROS: a Trojan horse that induces DNA damage A new role of ROS related to transcriptional output has been recently highlighted