Tirzepatide is FDA-approved (for diabetes and weight loss, depending on the brand) and works as a dual-agonist, targeting GLP-1 and GIP receptors to reduce appetite, improve insulin response, and support weight loss
Effective treatments for neurological disorders are still lacking, primarily due to the presence of the blood-brain barrier (BBB), a unique and selective endothelial barrier that protects against neurotoxic substances, as well as prevents the movement of xenobiotics into the CNS, including pharmacological agents (Pardridge, 2005)
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Rhodiola rosea This adaptogenic herb helps balance cortisol and improve mental endurance during stress
2023;903 doi: 10.1016/j.scitotenv.2023.166106