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Glutamate can also be catabolized into ammonium in the mitochondria and then enters the urea cycle. We note that neither glutamate nor glutamine itself was statistically different between controls and participants with ME/CFS at D1PRE ( P = 0.4 and P = 0.9 respectively) and throughout the time points (Supplemental Table 4)

Preclinical mitogenic concern Tomas et al

The presence of the second active-site cysteinyl residue in PfGrx improves the reactivity of the ternary complex but does not form an intramolecular disulfide bond in contrast to a dithiol mechanism

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