glutathione and parasites Thioredoxin Reductase from Schistosoma mansoni: An Essential Parasite Enzyme a Key Drug Target Possible mechanisms of haem toxicity

Cannabinoid signaling and liver therapeutics

498 In macrophages, LXR, which is highly expressed, serves as a crucial link between cholesterol metabolism and inflammatory responses

As the most famous natural antioxidant, glutathione certainly has an impressive list of roles in the well-being of the human body: Pulls the reins on cell multiplication and cell death Gets rid of mercury from cells Helps the regeneration of vitamins E and C Acts as a detoxifying agent Helps with the metabolism of nutrients Keeps the immune system working properly Numerous studies have shown that low levels of glutathione are associated with oxidative stress, which, in turn, plays a huge role in the onset or progression of many diseases

Johansson AS, Ridderstrm M, Mannervik B

doi: 10.1158/0008-5472.CAN-07-2593

Further functional validation experiments clarified the regulatory logic between these two molecules