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These findings indicate that TfR is a key mediator of ferroptosis in GBM, suggesting that targeting TfR with compounds like fucoxanthin could offer a promising therapeutic strategy against GBM by inducing ferroptosis
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In mitochondria, LA is a vital cofactor for several enzymes (the oxoglutarate dehydrogenase complex [OGDC], pyruvate dehydrogenase complex [PDHC], branched-chain -ketoacid dehydrogenase complex [BCKDC]) that contribute to aerobic metabolism and nucleic acid synthesis [32, 33]
For example, a powdered antibiotic or peptide vial instructions may say add X mL sterile water for injection. In many cases, practitioners use bacteriostatic water (when allowed) so that one vial can serve multiple doses
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