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Description

Glu170 is too far away from the active site to directly affect the interaction between HEDS and the cysteine thiolate

In fact, it was designed to avoid the appetite stimulation seen with some earlier peptides

Most research facilities do not have in-house LC-MS/MS capability and must send samples to specialized contract labs, which introduces logistical complexity and cost

The compound has substantial cosmetic-ingredient regulated use in topical preparations under the relevant cosmetic regulatory frameworks, distinct from any pharmaceutical approval