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Using IV therapy to administer high doses of Vitamin C has been shown to reduce this toxicity, decreasing infections, bone marrow toxicity, liver and pancreatic toxicity, gastrointestinal toxicity, and dermatological toxicity

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Mynarska E, et al

Chronic hyperinsulinemia promotes human hepatocyte senescence

For psoriasis, nasal delivery could be relevant for peptides that need systemic distribution but are poorly absorbed orally

These are legitimate scientific measurements, but they are surrogate readouts, not clinical outcomes that patients or clinicians experience