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Acute metabolic effects and half-lives of intravenously administered insulinlike growth factors I and II in normal and hypophysectomized rats

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Immunofluorescence staining and quantification revealed no significant difference in acetylated-tubulin levels among the WT, S1025D, and S1025A groups (Figure 4D, E)

Results showed 55.8% reduction in wrinkle volume compared to control serum and 32.8% reduction in wrinkle depth