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In a separate study, Abu Danso et al

In contrast, other cells of the body suffered only indirect damage, as tobacco smoking seems to affect key mechanisms in these cells that in turn mutate DNA. The study revealed at least five distinct processes of DNA damage due to cigarette smoking

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Before now, we had a large body of epidemiological evidence linking smoking with cancer, but now we can actually observe and quantify the molecular changes in the DNA due to cigarette smoking

Because it stimulates dopamine release, depressed patients often resort to smoking (or vaping) to mitigate the adverse effects of stressful stimuli. Depressed smokers have reported mood improvements that depression-free smokers don't experience after finishing a cigarette