The in vitro data demonstrated that AOD9604 increases 3-AR expression in fat cells, contributing to enhanced lipolytic sensitivity
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As blood pressure increases, plasma levels of C-reactive protein (CRP) [206, 207]and cytokines (particularly IL-6, tumor necrosis factor (TNF) [208, 209], and IL-1, IL-18, and CC chemokine ligand 2 (CCL2) also elevate [210,211,212,213]
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