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Mitochondrial complex I

10.2174/1570163814666170727130003 81 SheaB.SwindenM

Enzymatic antioxidants are cellular proteins that catalytically remove radicals or reactive species to protect against oxidative stress

82 The promising mechanism of action of TLK286 and its positive preclinical data have sparked a series of clinical trials where the prodrugs have been applied alone or in combination with other standard chemotherapeutic agents

The Smith patent references the treatment of disease by restoration of antioxidant function, but does not reference improvement by restoring the function of the remethylation of methionine, not does it reference the use of reduced glutathione as a single entity in a liposome