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in Current Pharmaceutical Design documented BPC-157s multi-organ protective effects across more than two decades of preclinical research, with particular focus on its remarkable stability in gastric acid a property that distinguishes it from most biologically active peptides and enables oral delivery studies in animal models [1]
Parseghian CM, Parikh NU, Wu JY, Jiang ZQ, Henderson L, Tian F, Pastor B, Ychou M, Raghav K, Dasari A, Fogelman DR, Katsiampoura AD, Menter DG, Wolff RA, Eng C, Overman MJ, Thierry AR, Gallick GE, Kopetz S
One study found that a selective mammalian target of rapamycin complex 1/2 (mTOR1/2) dual inhibitor could enhance oxaliplatin-induced apoptosis by down-regulating the expression of p-gp (23)
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