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Epigenetic mechanisms, including histone modifications and DNA accessibility, regulate transcription initiation (Reynolds et al., 2016)

Over past few decades, free radical theory has significantly stimulated interest in the role of dietary antioxidants in preventing many human diseases like cancer, stroke, atherosclerosis, rheumatoid arthritis, diabetes and neurodegeneration 7

Once inflammation and oxidative stress start building up and deplete antioxidants like glutathione, it can cause damage to our cells

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In parallel with serum enzyme activities, more severe necrosis was observed in TPH1 null mice than in wild type mice after acetaminophen administration (Figure 1B)

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