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A larger clinical trial randomly assigned more than 500 patients with type 2 diabetes and symptomatic peripheral neuropathy to one of the following treatments: (i) 600 mg/day of intravenous lipoic acid for three weeks followed by 1,800 mg/day of oral lipoic acid for six months, (ii) 600 mg/day of intravenous lipoic acid for three weeks followed by oral placebo for six months, or (iii) intravenous placebo for three weeks followed by oral placebo for six months (76)

doi: 10.5935/1518-0557.20180003

WarelowTPOkeMSchoepp-CothenetBDahlJUBruselatNSivalingamGNet al

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DOI: 10.1089/ars.2017.7051 93