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In a mouse model of ALS (SOD1 G93A), 5-MTHF levels are significantly reduced in the plasma, spinal cord, and cortex at the pre-symptomatic stage, whereas Hcy levels are markedly increased following the onset of motor symptoms in the ALS mice [192]
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The feeding medium contained 500 g/L glucose and 25 g/L MgSO 4 7H 2 O
Lee C, Kim J, Jung Y
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