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Studies show FOXO4-DRI treatment reduces senescent cell burden by 50-70% in various tissues including liver, kidney, and adipose tissue within weeks of treatment initiation in aged mice

Published research documents their roles in extracellular matrix regulation, fibroblast activity, and growth factor expression

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In addition, other studies indicate that dyspnea, autonomic symptoms, post-traumatic stress and fibromyalgia symptoms (muscle aches, myalgia, and articular pain) are common [109,110,111]

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