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Divergent findings across studies reflect variations in dosing, model systems, disease context, and timing

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The infusion skips that stage and delivers the full dose directly into the bloodstream

Study design In this prospective cross-over study, five female and five male NZW rabbits each received four treatments with buprenorphine (Vetergesic vet, 0.3 mg/mL, Orion Pharma, Danderyd, Sweden), with 2-week wash-out periods between treatments