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CMV -Cre), together with mitochondrial metabolomics and whole-cell tracing in the presence of D 9 -TML, revealed that SLC25A45 depletion led to markedly reduced mitochondrial uptake of D 9 -labeled TML

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* N represents the number of participants that finished the treatment in the clinical trial and had a blood draw for the biomarkers under study

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Physiologically, it serves as an essential cofactor in the conversion of methylmalonyl-CoA to succinyl-CoAa substrate for the tricarboxylic acid cycleand plays fundamental roles in DNA and protein synthesis, methylation cycles, and folic acid metabolism (73)

Bulk Drug Substances Nominated for Use in Compounding Under Section 503A (Categoras 503A